Jie Zhou

This study identifies GLUT1 as a driver of immunotherapy resistance in ESCC by epigenetically suppressing senescence and reveals dietary glucose restriction as a potential strategy to enhance immunotherapy efficacy.

AutoPELSA automates the PELSA workflow for proteome-wide ligand-protein interaction detection, enabling high-throughput analysis of both strong and low-affinity ligands.

This study identifies the complete biosynthetic pathway of camptothecin, discovers missing enzymes, and validates the pathway through heterologous reconstruction in yeast.

This paper develops a microfluidic platform to profile drug responses in NSCLC patient-derived organoids, showing that microenvironmental cues affect therapeutic responses and resistance mechanisms.

This study identifies Kindlin-2-Moesin interaction as a regulator of sprouting angiogenesis by modulating endothelial membrane tension and VEGF signaling.