Functional characterization of RebL1 highlights the evolutionary conservation of oncogenic activities of the RBBP4/7 orthologue in Tetrahymena thermophila
Syed Nabeel‐Shah, Jyoti Garg, Alejandro Saettone, Kanwal Ashraf, Hyunmin Lee, Suzanne Wahab, Nujhat Ahmed, Jacob L. Fine, Joanna Derynck, Shuye Pu, Marcelo Ponce, Edyta Marcon, Zhaolei Zhang, Jack F. Greenblatt, Ronald E. Pearlman, , Jeffrey Fillingham
The paper identifies RebL1 as an orthologue of human RBBP4/7 in Tetrahymena thermophila, showing its role in epigenetic regulation and oncogenic functions across species.
Nucleic Acids Research · May 4, 2021Peer-reviewedMolecular Biology