SARS-CoV-2 Nucleocapsid protein attenuates stress granule formation and alters gene expression via direct interaction with host mRNAs
Syed Nabeel‐Shah, Hyunmin Lee, Nujhat Ahmed, Giovanni L. Burke, Shaghayegh Farhangmehr, Kanwal Ashraf, Shuye Pu, Ulrich Braunschweig, Guoqing Zhong, Hong Wei, Hua Tang, Jianyi Yang, Edyta Marcon, Benjamin J. Blencowe, Zhaolei Zhang, Jack F. Greenblatt
This study identifies SARS-CoV-2 N protein interactions with host proteins and mRNAs, showing it attenuates stress granule formation and alters gene expression.
iScience · Dec 4, 2021Peer-reviewedMolecular Biology