Author
Florida State University
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
3 papers
Recent·Most cited
Johanna E Papa, Arthur Carl Whittington, Brian G. Miller
This study identifies the evolutionary emergence of redox sensitivity in vertebrate glucokinases through conformational expansion and cysteine residue acquisition.
Joshua I. Santiago, Carolin Freye, S. Shirin Kamalaldinezabadi…·Brian G. Miller
This study identifies a single mutation that enables GKRP to gain small-molecule allostery through structural co-optation, without requiring new genetic material.
S. Shirin Kamalaldinezabadi, Joshua I. Santiago, Johanna E Papa…·Brian G. Miller
This paper reconstructs extinct glucokinase (GCK) and glucokinase regulatory protein (GKRP) to study the evolutionary origins of protein regulation in vertebrate glucose homeostasis.