Author

John Montilla

Drexel University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Peter J. GaskilliD· 2 shared Stephanie M. MattiD· 2 shared Amirali AmirfallahiD· 1 shared Anneliese M. FaustinoiD· 1 shared Breana ChanneriD· 1 shared Erin O. Curley· 1 shared Howard S. FoxiD· 1 shared Hsin-Yao TangiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Peter J. GaskillORCID

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2 papers

Recent·Most cited

Epigenetic Regulation of Inflammation by Dopamine in Primary Human Macrophages

Yash Agarwal, Margish D. Ramani, Samyuktha Manikandan, Kimberly A. Bonar, John Montilla, Peter J. Gaskill, Stephanie M. Matt

This study shows dopamine modulates macrophage inflammation through epigenetic changes, including DNA methylation and histone modifications, and highlights individual variability in response.

Frontiers in Immunology · Jun 26, 2026Peer-reviewedImmunology

It's Not Rewarding for Mitochondria: Dopamine-Induced Mitochondrial Dysfunction Activates cGAS-STING to Drive IL-6 Secretion in Macrophages

Marzieh Daniali, Breana Channer, Erin O. Curley, Amirali Amirfallah, Taylor Kist, John Montilla, Stephanie Kosashvili, Lexi Sheldon, Kelly L. Stauch, Joshua G. Jackson, Anneliese M. Faustino, Thomas Beer, Hsin-Yao Tang, Stephanie M. Matt, Will Dampier, , Peter J. Gaskill

This paper identifies a pathway where dopamine induces mitochondrial dysfunction in macrophages, leading to IL-6 secretion via the cGAS-STING pathway.

bioRxiv · Apr 25, 2026 · PreprintImmunology