Author

Lexi Sheldon

Nebraska Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Immunology· 2

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Howard S. FoxiD· 2 shared Marzieh DanialiiD· 2 shared Peter J. GaskilliD· 2 shared Taylor Kist· 2 shared Amirali AmirfallahiD· 1 shared Anneliese M. FaustinoiD· 1 shared Breana ChanneriD· 1 shared Erin O. Curley· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Howard S. FoxORCID

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2 papers

Recent·Most cited

It's Not Rewarding for Mitochondria: Dopamine-Induced Mitochondrial Dysfunction Activates cGAS-STING to Drive IL-6 Secretion in Macrophages

Marzieh Daniali, Breana Channer, Erin O. Curley, Amirali Amirfallah, Taylor Kist, John Montilla, Stephanie Kosashvili, Lexi Sheldon, Kelly L. Stauch, Joshua G. Jackson, Anneliese M. Faustino, Thomas Beer, Hsin-Yao Tang, Stephanie M. Matt, Will Dampier, , Peter J. Gaskill

This paper identifies a pathway where dopamine induces mitochondrial dysfunction in macrophages, leading to IL-6 secretion via the cGAS-STING pathway.

bioRxiv · Apr 25, 2026 · PreprintImmunology

Cocaine Acts Through Sigma-1 to Enhance HIV Infection of Microglia

Oluwatofunmi Oteju, Xiaoke Xu, Taylor Kist, Katy M. Emanuel, Lexi Sheldon, Marzieh Daniali, Meng Niu, Howard S. Fox, Peter J. Gaskill

This study shows cocaine enhances HIV infection of microglia via sigma-1 activation, which modulates the UPR to boost viral replication and immune evasion.

bioRxiv · Aug 6, 2025 · PreprintImmunology