Author

John Paul Schell

Karolinska University Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Cheng ZhaoiD· 2 shared Fredrik LanneriD· 2 shared Jere Weltner· 2 shared Laura Baqué-VidaliD· 2 shared Sophie Petropoulos AiD· 2 shared Álvaro Plaza ReyesiD· 1 shared Angelo Salazar ManteroiD· 1 shared Åsa K. BjörklundiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersDevelopmental Biology

Cheng ZhaoORCID

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2 papers

Recent·Most cited

A Comprehensive Human Embryogenesis Reference Tool using Single-Cell RNA-Sequencing Data

Cheng Zhao, Álvaro Plaza Reyes, John Paul Schell, Jere Weltner, N. M. Ortega, Yi Zheng, Åsa K. Björklund, Laura Baqué-Vidal, Joonas Sokka, Ras Trokovic, Brian Cox, Janet Rossant, Jianping Fu, Sophie Petropoulos A, Fredrik Lanner

The paper develops a comprehensive reference tool for human embryogenesis using integrated single-cell RNA-sequencing data to benchmark embryo models.

Nature Methods · Nov 14, 2024Peer-reviewedDevelopmental Biology

Polycomb Repressive Complex 2 shields naïve human pluripotent cells from trophectoderm differentiation

B. Mohana Kumar, Carmen Navarro, Nerges Winblad, John Paul Schell, Cheng Zhao, Jere Weltner, Laura Baqué-Vidal, Angelo Salazar Mantero, Sophie Petropoulos A, Fredrik Lanner, Simon J. Elsässer

This study shows that PRC2 restricts naive pluripotent stem cells from differentiating into trophectoderm by maintaining bivalent promoters and H3K27me3 methylation.

Nature Cell Biology · May 30, 2022Peer-reviewedDevelopmental Biology