Author

Meghan Schilthuis

Van Andel InstituteORCID 0000-0002-3871-4039Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Assay:DNA methylation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Assay:metagenomics· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Bryan A. KillingeriD· 2 shared Elizabeth EnsinkiD· 2 shared Irving E. VegaiD· 2 shared Jared A. LampiD· 2 shared Lena BrundiniD· 2 shared Patrik BrundiniD· 2 shared Viviane LabrieiD· 2 shared Ali YılmaziD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersNeuroscience

Bryan A. KillingerORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Aggregation-prone alpha-synuclein proteoforms and dysregulated molecular signatures in the vermiform appendix of synucleinopathy patients

Ehraz Anis, Saima Zameer, Josh Wierenga, Peipei Li, Jacek W. Sikora, Juozas Gordevičius, Meghan Schilthuis, Richard D. LeDuc, Jeffrey H. Kordower, Michelle A. Pinho, Sandra Pritzkow, Claudio A. Soto, Patrik Brundin, Lena Brundin, Bryan A. Killinger

The paper examines alpha-synuclein aggregation and molecular changes in appendix tissues from synucleinopathy patients compared to controls.

bioRxiv · Oct 7, 2025 · PreprintNeuroscience

Gut microbiome dysbiosis is associated with elevated toxic bile acids in Parkinson's disease

Peipei Li, Bryan A. Killinger, Ian Beddows, Elizabeth Ensink, Ali Yılmaz, Noah Lubben, Jared A. Lamp, Meghan Schilthuis, Irving E. Vega, Markus Britschgi, John Andrew Pospisilik, Patrik Brundin, Lena Brundin, Stewart Francis Graham, Viviane Labrie

This study identifies elevated toxic bile acids in Parkinson's disease patients and links them to gut microbiome dysbiosis and early biliary changes.

bioRxiv · Sep 26, 2020 · PreprintNeuroscience

Epigenetic contributions to hemisphere asymmetry in healthy brain, aging, and Parkinson’s disease

Peipei Li, Elizabeth Ensink, Sean Lang, Lee L. Marshall, Meghan Schilthuis, Jared A. Lamp, Irving E. Vega, Viviane Labrie

This study identifies epigenetic differences in hemispheric asymmetry in healthy brains, Parkinson’s disease, and aging, showing increased asymmetry in PD and its association with disease progression.

bioRxiv · Oct 7, 2019 · PreprintNeuroscience