Author

Joshua D. Beaver

The University of Texas Southwestern Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:protein structure· 2 Research Focus:protein structure prediction· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Brian D. HittiD· 2 shared Charles L. WhiteiD· 2 shared Marc I. DiamondiD· 2 shared Ankit GuptaiD· 1 shared Bret M. EversiD· 1 shared Byron W. CaugheyiD· 1 shared Carol A. TammingaiD· 1 shared Efrosini Artikis· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersNeuroscience

Brian D. HittORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Tau seeding without tauopathy

Michael LaCroix, Efrosini Artikis, Brian D. Hitt, Joshua D. Beaver, Sandi Jo Estill, Kelly Gleason, Carol A. Tamminga, Bret M. Evers, Charles L. White, Byron W. Caughey, Marc I. Diamond

The paper detects seeding activity of tau assemblies in healthy human brains, suggesting normal physiological tau function that may contribute to disease when disrupted.

Journal of Biological Chemistry · Dec 9, 2023Peer-reviewedNeuroscience

Anti-tau antibodies targeting a conformation-dependent epitope selectively bind seeds

Brian D. Hitt, Ankit Gupta, Ruhar Singh, Ting Yang, Joshua D. Beaver, Ping Shang, Charles L. White, Łukasz A. Joachimiak, Marc I. Diamond

The paper develops anti-tau antibodies that selectively bind pathological tau seeds in neurodegenerative diseases, supporting a model of conformational change at P301.

Journal of Biological Chemistry · Sep 13, 2023Peer-reviewedNeuroscience