Author

Joshua M. Bradner

Columbia University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Organism:C. elegans· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

Gary Wright MilleriD· 2 shared Meghan L. BucheriD· 2 shared Michelle A. JohnsoniD· 2 shared Amy R. DunniD· 1 shared Dean P. JonesiD· 1 shared Douglas Ian WalkeriD· 1 shared Fion K. Lau· 1 shared James P. BurkettiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Gary Wright MillerORCID

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Author profile →

2 papers

Recent·Most cited

Synaptic vesicle glycoprotein 2C enhances vesicular storage of dopamine and counters dopaminergic toxicity

Meghan L. Bucher, Amy R. Dunn, Joshua M. Bradner, Kristen Stout Egerton, James P. Burkett, Michelle A. Johnson, Gary Wright Miller

This study shows that SV2C enhances dopamine and neurotoxicant storage in vesicles, reducing dopaminergic neuron vulnerability.

European Journal of Neuroscience · Mar 26, 2024Peer-reviewedNeuroscience

Genetic or toxicant induced disruption of vesicular monoamine storage and global metabolic profiling in Caenorhabditis elegans

Joshua M. Bradner, Vrinda Kalia, Fion K. Lau, Monica Sharma, Meghan L. Bucher, Michelle A. Johnson, Merry Chen, Douglas Ian Walker, Dean P. Jones, Gary Wright Miller

This study investigates the effects of reduced VMAT activity in C. elegans, showing increased sensitivity to MPP+ and metabolic changes, suggesting conserved monoamine function and potential for metabolomics in disease research.

Toxicological Sciences · Jan 22, 2021Peer-reviewedNeuroscience