Vrinda Kalia

The paper identifies sex- and Alzheimer's disease stage-specific genetic regulators of plasma metabolites and their associations with biomarkers.

This paper identifies swip-10's role in systemic copper homeostasis in C. elegans, linking it to mitochondrial function, oxidative stress, and neurodegeneration.

The paper introduces GAIT-GM, a Galaxy tool for multi-omics analysis, and finds a link between branched-chain amino acid metabolism and cholinergic neuron defects in a C. elegans Parkinson's disease model.

This study investigates the effects of reduced VMAT activity in C. elegans, showing increased sensitivity to MPP+ and metabolic changes, suggesting conserved monoamine function and potential for metabolomics in disease research.

This study shows that metabolic defects in C. elegans lead to hyperactive mitochondria and Parkinson's-like traits, with metformin improving motor function and reducing neurodegeneration.