Investigating Bio-Nano Interactions of PEGylated Cationic Polyamidoamine (PAMAM) Dendrimers within Synovial Joints
Simone A. Douglas-Green, Juan A. Aleman, Victor M Dampty, Bhuvna Murthy, Brandon Johnston, Joon Ho Park, Alan Jay Grodzinsky, Paula Therese Hammond
This study investigates how PEGylated cationic PAMAM dendrimers interact with proteins in synovial fluid and how these interactions affect their uptake in cartilage and internalization by chondrocytes.
bioRxiv · Aug 9, 2025 · PreprintBioengineering