Simone A. Douglas-Green

This study shows that the outer polyion layer of layer-by-layer nanoparticles affects protein corona formation, which influences their biodistribution and therapeutic efficacy.

ProCAST is an R-based framework for analyzing protein corona proteomics data, enabling clustering, visualization, and functional interpretation of adsorbed proteins.

This study investigates how PEGylated cationic PAMAM dendrimers interact with proteins in synovial fluid and how these interactions affect their uptake in cartilage and internalization by chondrocytes.