Layer-by-Layer Nanoparticle Outer Polyion Impacts Protein Corona Formation
Tamara G. Dacoba, Simone A. Douglas-Green, Bhuvna Murthy, Alfonso D Restrepo, Zavian Strom, Margaret M. Billingsley, Alexander D. Stoneman, Mae L. Pryor, Paula Therese Hammond
This study shows that the outer polyion layer of layer-by-layer nanoparticles affects protein corona formation, which influences their biodistribution and therapeutic efficacy.
Biomaterials · Aug 28, 2026Peer-reviewedBioengineering