Joon Ho Park

Investigating Bio-Nano Interactions of PEGylated Cationic Polyamidoamine (PAMAM) Dendrimers within Synovial Joints

This study investigates how PEGylated cationic PAMAM dendrimers interact with proteins in synovial fluid and how these interactions affect their uptake in cartilage and internalization by chondrocytes.

Lab evolution, transcriptomics, and modeling reveal mechanisms of paraquat tolerance

The paper uses adaptive laboratory evolution and transcriptomic analysis to identify six mechanisms of paraquat tolerance in E. coli.

Experimental evolution reveals the genetic basis and systems biology of superoxide stress tolerance

This study uses adaptive laboratory evolution to generate E. coli strains with increased superoxide stress tolerance and identifies genetic and transcriptomic mechanisms underlying this adaptation.

Cellular responses to reactive oxygen species can be predicted on multiple biological scales from molecular mechanisms

The paper develops a quantitative framework to predict ROS stress responses in E. coli across molecular, network, and genetic levels.