Author

Jessica A. Beck

National Institutes of HealthORCID 0000-0002-0145-7606Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 3 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:drug response / drug discovery· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Assay:imaging· 1 Assay:metagenomics· 1

Frequent Co-Authors

Amy Kathleen LeBlanciD· 2 shared Curtis C. HarrisiD· 2 shared Alex Valm· 1 shared Alexis N. Hokenstad· 1 shared Amiran H. Dzutsev· 1 shared Ana I. Robles· 1 shared Archana S. Bhat· 1 shared Ashely J. Vargas· 1 shared

Activity by Year

2018-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

Amy Kathleen LeBlancORCID

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Author profile →

4 papers

Recent·Most cited

Biodistribution-Driven Discovery Identifies a Glycosidase-Cleavable Linker to Reprogram Radiotheranostics

Woong Hee Lee, Sai Reddy Doda, Kwamena E. Baidoo, Divya Nambiar, Joon‐Yong Chung, Stephen Adler, Elijah F. Edmondson, Yuki Ueda, Satoshi Omiya, Xiaoyi Li, Hima Makala, Julia Sheehan‐Klenk, Stanley Fayn, Orit Jacobson, Eric Lindberg, , Freddy E. Escorcia

A β-galactose-cleavable linker reduces kidney toxicity, enhances tumor targeting and therapeutic efficacy in radiopharmaceutical therapy.

bioRxiv · Sep 11, 2025 · PreprintCancer Biology

Spatial profiling identifies regionally distinct microenvironments and targetable immunosuppressive mechanisms in pediatric osteosarcoma pulmonary metastases.

Jason Eigenbrood, Nathan W. Wong, Paul W. Mallory, Janice S. Pereira, Demond Williams, Douglass W. Morris-II, Jessica A. Beck, James C. Cronk, Carly M. Sayers, Monica Mendez, Linus Kaiser, Julie Galindo, Jatinder Singh, Ashley Cardamone, Milind M. Pore, , Troy A. McEachron

Visium profiling of nine pediatric osteosarcoma pulmonary metastases reveals a conserved granuloma-like architecture: inflamed macrophage-rich periphery, collagen capsule, inflammation-poor core, and CXCR4 as candidate target.

Cancer Research · Apr 2, 2025Peer-reviewedCancer Biology✦ In-depth digest

Δ133p53α Protects Human Astrocytes from Amyloid-Beta Induced Senescence and Neurotoxicity

Kyra Ungerleider, Jessica A. Beck, Delphine Lissa, Sebastien M. Joruiz, Izumi Horikawa, Curtis C. Harris

This paper shows that Δ133p53α protects human astrocytes from amyloid-beta-induced senescence and neurotoxicity by preventing DNA damage and SASP.

bioRxiv · May 17, 2021Neuroscience

Microbiome-TP53 Gene Interaction in Human Lung Cancer

K. Leigh Greathouse, James R. White, Ashely J. Vargas, Valery V. Bliskovsky, Jessica A. Beck, Natalia von Muhlinen, Eric C. Polley, Elise D. Bowman, Mohammed A. Khan, Ana I. Robles, Tomer Cooks, Bríd M. Ryan, Amiran H. Dzutsev, Giorgio Trinchieri, Marbin A. Pineda, , Curtis C. Harris

This study identifies a microbiome-TP53 interaction in squamous cell lung cancer, showing Acidovorax enrichment in smokers with TP53 mutations.

bioRxiv · Feb 28, 2018 · PreprintCancer Biology