Species-level bacterial community profiling of the healthy sinonasal microbiome using Pacific Biosciences sequencing of full-length 16S rRNA genes
Joshua P. Earl, Nithin D. Adappa, Jarosław E. Król, Archana S. Bhat, Sergey V. Balashov, Rachel L. Ehrlich, James N. Palmer, Alan D. Workman, Mariel T. Blasetti, Bhaswati Sen, Jocelyn A. Hammond, Noam A. Cohen, Garth D. Ehrlich, Joshua Chang Mell
The paper presents a pipeline using PacBio CCS to sequence full-length 16S rRNA genes for species-level microbiome analysis, showing high accuracy in mock communities and variation in sinonasal microbiomes.
Microbiome · Oct 23, 2018Peer-reviewedBioinformatics