Origin of the GPR15LG-GPR15 signaling axis in ancient fish ancestors
Jun-Jie Yao, Jie Yu, Hao‐Zheng Li, Juan-Juan Wang, Ya-Li Liu, Zhan‐Yun Guo
This study identifies and functionally characterizes GPR15LG orthologs in fish, showing their conserved signaling with GPR15 and evolutionary origin in ancient fish ancestors.
bioRxiv · Jun 4, 2026 · PreprintBiochemistry