Author

Justin B. Klee

Amylyx Pharmaceuticals, Inc. (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Anton M. SimeonoviD· 1 shared CRIS M. BROWN· 1 shared Fumihiko UranoiD· 1 shared Jeffrey R. MillmaniD· 1 shared Joseph Ekstein· 1 shared Joshua N. CoheniD· 1 shared Kelly KriesiD· 1 shared Kent L. Leslie· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

Anton M. SimeonovORCID

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1 paper

Recent·Most cited

Genotype-phenotype correlation analysis and therapeutic development using a patient stem cell-derived disease model of Wolfram syndrome

Rie Asada Kitamura, Kristina G. Maxwell, Wenjuan Ye, Kelly Kries, CRIS M. BROWN, Punn Augsornworawat, Yoel Hirsch, Martin M. Johansson, Tzvi Weiden, Joseph Ekstein, Joshua N. Cohen, Justin B. Klee, Kent L. Leslie, Anton M. Simeonov, Mark J. Henderson, , Fumihiko Urano

This study uses a patient-derived stem cell model to show that a specific WFS1 variant causes mild Wolfram syndrome, which can be treated with chemical chaperones.

bioRxiv · Nov 7, 2021 · PreprintGenetics