Author

Rie Asada Kitamura

Washington University in St. LouisORCID 0000-0001-8347-6909Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Fumihiko UranoiD· 2 shared Alessandro UstioneiD· 1 shared Anton M. SimeonoviD· 1 shared CRIS M. BROWN· 1 shared David W. PistoniD· 1 shared Devynn HummeliD· 1 shared Jeffrey R. MillmaniD· 1 shared Joseph Ekstein· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMolecular Biology

Fumihiko UranoORCID

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2 papers

Recent·Most cited

Dual Role of Neuroplastin in Pancreatic Beta Cells: Regulating Insulin Secretion and Promoting Islet Inflammation

Rie Asada Kitamura, Devynn Hummel, Alessandro Ustione, David W. Piston, Fumihiko Urano

This study identifies Neuroplastin as a binding partner of MANF in pancreatic beta cells, showing it regulates insulin secretion, proliferation, and inflammation, with MANF counteracting these effects.

Proceedings of the National Academy of Sciences · Aug 6, 2024Peer-reviewedMolecular Biology

Genotype-phenotype correlation analysis and therapeutic development using a patient stem cell-derived disease model of Wolfram syndrome

Rie Asada Kitamura, Kristina G. Maxwell, Wenjuan Ye, Kelly Kries, CRIS M. BROWN, Punn Augsornworawat, Yoel Hirsch, Martin M. Johansson, Tzvi Weiden, Joseph Ekstein, Joshua N. Cohen, Justin B. Klee, Kent L. Leslie, Anton M. Simeonov, Mark J. Henderson, , Fumihiko Urano

This study uses a patient-derived stem cell model to show that a specific WFS1 variant causes mild Wolfram syndrome, which can be treated with chemical chaperones.

bioRxiv · Nov 7, 2021 · PreprintGenetics