Predicting Early Diabetic Kidney Disease Using a 3D Mesangial Model and Bayesian Mechano-Chemical Stratification
B. Ghosh, F. Niknam, N. Kumar, K. A. Fenton, K. Agarwal
bioRxiv · Dec 10, 2023 · PreprintBiophysics
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9 papers
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B. Ghosh, F. Niknam, N. Kumar, K. A. Fenton, K. Agarwal
bioRxiv · Dec 10, 2023 · PreprintBiophysics
L. E. Villegas-Hernandez, V. K. Dubey, H. Mao, M. Pradhan, J.-C. Tinguely, D. H. Hansen, S. Acuna, B. Zapotoczny, K. Agarwal, M. Nystad, G. Acharya, K. A. Fenton, H. E. Danielsen, B. S. Ahluwalia
This paper introduces a photonic chip-based microscopy method for super-resolution imaging of FFPE tissue sections, demonstrating improved contrast and compatibility with histological workflows.
bioRxiv · Jun 14, 2023 · PreprintPathology
C. Woolsey, R. W. Cross, K. N. Agans, V. Borisevich, D. J. Deer, J. B. Geisbert, C. Gerardi, T. E. Lantham, K. A. Fenton, M. Egan, J. H. Eldridge, T. W. Geisbert, D. Matassov
This paper shows a highly attenuated rVSV-based vaccine protects nonhuman primates against lethal Marburg virus challenge when administered up to 1 week before exposure.
bioRxiv · Jan 22, 2022Microbiology
R. W. Cross, A. N. Prasad, C. Woolsey, K. N. Agans, V. Borisevich, N. S. Dobias, J. E. Comer, D. J. Deer, J. B. Geisbert, A. Rasmussen, W. I. Lipkin, K. A. Fenton, T. W. Geisbert
This study examines the natural history of Ebola virus infection in nonhuman primates after conjunctival exposure, finding that lower doses result in delayed disease and reduced mortality.
bioRxiv · Dec 29, 2021Microbiology
L. E. Villegas-Hernandez, V. K. Dubey, M. Nystad, J.-C. Tinguely, D. A. Coucheron, F. T. Dullo, A. Priyadarshi, S. Acuna, J. M. Mateos, G. Barmettler, U. Ziegler, A.-M. K. Hovd, K. A. Fenton, G. Acharya, K. Agarwal, B. S. Ahluwalia
This study validates a photonic chip-based super-resolution microscopy platform for high-throughput multimodal histopathological analysis of cryopreserved tissue samples.
bioRxiv · May 6, 2021Pathology
r. cross, A. N. Prasad, V. Borisevich, C. Woolsey, K. N. Agans, D. J. Deer, N. S. Dobias, J. B. Geisbert, K. A. Fenton, T. W. Geisbert
This study shows that convalescent sera with high neutralizing antibody titers reduce SARS-CoV-2 viral load and disease severity in African green monkeys.
bioRxiv · Oct 14, 2020Microbiology
C. B. Woolsey, V. Borisevich, A. N. Prasad, K. N. Agans, D. J. Deer, N. S. Dobias, J. C. Heymann, S. L. Foster, C. B. Levine, L. Medina, K. Melody, J. B. Geisbert, K. A. Fenton, T. W. Geisbert, R. W. Cross
This study establishes an African green monkey model for COVID-19, showing high SARS-CoV-2 replication and severe respiratory disease with lower viral doses than in other NHP species.
bioRxiv · May 17, 2020 · PreprintMicrobiology
A. D. Jayaprakash, A. J. Ronk, A. N. Prasad, M. F. Covington, K. R. Stein, T. M. Schwarz, S. Hekmaty, K. A. Fenton, T. W. Geisbert, C. F. Basler, A. Bukreyev, R. Sachidanandam
This study investigates how Marburg and Ebola viruses elicit a complex, muted inflammatory response in bats, revealing mechanisms that may explain their non-pathogenicity in these animals.
bioRxiv · Apr 13, 2020Microbiology
R. W. Cross, Z. A. Bornholdt, A. N. Prasad, J. B. Geisbert, V. Borisevich, K. N. Agans, D. J. Deer, K. Melody, K. A. Fenton, H. Feldmann, A. Sprecher, T. W. Geisbert
bioRxiv · Apr 1, 2020Microbiology