Author

K. A. Kuhn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:human· 4 Research Focus:differential expression· 3 Assay:metagenomics· 3 Assay:metabolomics· 2 Organism:mouse· 2

Frequent Co-Authors

A. Stahly· 2 shared K. D. Deane· 2 shared M. Chriswell· 2 shared M. K. Demoruelle· 2 shared M. L. Feser· 2 shared V. M. Holers· 2 shared A. Berlinberg· 1 shared A. Brar· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersImmunology

A. Stahly

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

MAIT cells drive chronic inflammation in a genetically diverse murine model of spontaneous colitis.

L. Loh, D. Orlicky, A. Spengler, C. Levens, S. Celli, J. Domenico, J. Klarquist, J. Onyiah, J. Matsuda, K. A. Kuhn, L. Gapin

This study investigates the role of MAIT cells in a genetically diverse mouse model of spontaneous colitis, finding that MAIT cells drive chronic inflammation and colonic pathology.

bioRxiv · Nov 29, 2023 · PreprintImmunology

Microbiota-dependent indole production is required for the development of collagen-induced arthritis

B. Seymour, B. Trent, B. Allen, A. Berlinberg, J. Tangchittsumran, W. Jubair, M. Chriswell, S. Liu, A. Ornelas Sanchez, A. Stahly, E. Alexeev, A. Dowdell, S. Sneed, S. Fechtner, J. Kofonow, , K. A. Kuhn

This study shows that microbiota-dependent indole production is essential for collagen-induced arthritis development and identifies potential therapeutic targets.

bioRxiv · Oct 13, 2023 · PreprintImmunology

Dual IgA/IgG family autoantibodies from individuals at-risk for rheumatoid arthritis identify an arthritogenic strain of Subdoligranulum

M. Chriswell, A. R. Lefferts, M. Clay, A. Hsu, J. Seifert, M. L. Feser, M. Maerz, C. Rims, M. Bloom, E. A. Bemis, M. K. Demoruelle, K. D. Deane, E. A. James, J. H. Buckner, W. H. Robinson, , K. A. Kuhn

Subdoligranulum spp. targeted by RA-relevant autoantibodies activate T cells in RA patients and induce autoantibodies and joint swelling in mice.

bioRxiv · Jun 9, 2022 · PreprintImmunology

A Novel Approach Towards Less Invasive Multi 'Omics Gut Analyses: A Pilot Study

A. J. Berlinberg, A. Brar, A. Stahly, M. E. Gerich, B. P. Fennimore, F. I. Scott, K. A. Kuhn

This study compares metatranscriptomic and metabolomic data from mucosal cytology brush sampling and intestinal biopsy in healthy participants, finding brush sampling is less invasive but metabolomics may require biopsy.

bioRxiv · Nov 24, 2021 · PreprintMicrobiology

Individuals at risk for developing rheumatoid arthritis harbor differential intestinal bacteriophage communities with distinct metabolic potential

M. R. Mangalea, D. Paez-Espino, K. A. Kieft, A. Chatterjee, J. A. Seifert, M. L. Feser, M. K. Demoruelle, M. E. Chriswell, A. Sakatos, K. Anantharaman, K. D. Deane, K. A. Kuhn, V. M. Holers, B. A. Duerkop

The paper identifies differential intestinal bacteriophage communities in individuals at risk for RA based on anti-CCP status, linking them to distinct metabolic potentials and potential roles in RA pathogenesis.

bioRxiv · Feb 3, 2021Microbiology