Author

E. A. James

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

C. Speake· 2 shared J. Kanyo· 2 shared K. C. Herold· 2 shared M.-L. Yang· 2 shared R. Gee· 2 shared T. Lam· 2 shared A. Hsu· 1 shared A. Perdigoto· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersImmunology

C. Speake

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Dual IgA/IgG family autoantibodies from individuals at-risk for rheumatoid arthritis identify an arthritogenic strain of Subdoligranulum

M. Chriswell, A. R. Lefferts, M. Clay, A. Hsu, J. Seifert, M. L. Feser, M. Maerz, C. Rims, M. Bloom, E. A. Bemis, M. K. Demoruelle, K. D. Deane, E. A. James, J. H. Buckner, W. H. Robinson, , K. A. Kuhn

Subdoligranulum spp. targeted by RA-relevant autoantibodies activate T cells in RA patients and induce autoantibodies and joint swelling in mice.

bioRxiv · Jun 9, 2022 · PreprintImmunology

Carbonyl Post-Translational Modification Associated with Early Onset Type 1 Diabetes Autoimmunity

M.-L. Yang, S. Connolly, R. Gee, T. Lam, J. Kanyo, S. G. Clarke, C. F. Clarke, E. A. James, C. Speake, C. Evans-Molina, L. Wen, K. C. Herold, M. Mamula

The paper identifies carbonylated P4Hb as an autoantigen in type 1 diabetes, detected before hyperglycemia in NOD mice and early human disease.

bioRxiv · Jun 15, 2021 · PreprintImmunology

Citrullination of glucokinase linked to autoimmune diabetes

M.-L. Yang, S. Horstman, R. Gee, P. Guyer, T. Lam, J. Kanyo, A. Perdigoto, C. Speake, C. J. Greenbaum, L. Overbergh, R. Kibbey, K. C. Herold, E. A. James, M. J. Mamula

This study identifies citrullination of glucokinase as an inflammatory-driven PTM that triggers autoimmunity and impairs glucose metabolism in Type 1 diabetes.

bioRxiv · Apr 28, 2021Immunology