Author

K. A. Ozeki

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Cell Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. Henke· 1 shared C. K. Glass· 1 shared C. R. Edillor· 1 shared E. D. Muse· 1 shared J. Bahadorani· 1 shared J. G. McDonald· 1 shared J. S. Seidman· 1 shared J. T. Roland· 1 shared

Activity by Year

2018-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

A. Henke

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1 paper

Recent·Most cited

Cell-specific discrimination of desmosterol and desmosterol mimetics confers selective regulation of LXR and SREBP pathways in macrophages

E. D. Muse, S. Yu, C. R. Edillor, J. Tao, N. J. Spann, T. D. Troutman, J. S. Seidman, A. Henke, J. T. Roland, K. A. Ozeki, J. G. McDonald, J. Bahadorani, S. Tsimikas, T. R. Grossman, M. S. Tremblay, C. K. Glass

This study shows that desmosterol and its mimetics selectively activate LXR in macrophages without inducing SREBP1c-mediated hypertriglyceridemia, unlike conventional LXR agonists.

bioRxiv · Feb 11, 2018Cell Biology