Author

K. Chinthalapudi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Organism:human· 2 Assay:structural biology· 2 Research Focus:cell type annotation· 1 Organism:Drosophila· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

S. Heissler· 2 shared A. Pedrosa· 1 shared A. S. Arora· 1 shared A. Suchenko· 1 shared C. Ibar· 1 shared D. J. Manstein· 1 shared H.-L. Huang· 1 shared J. Hammer· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersCell Biology

S. Heissler

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Author profile →

4 papers

Recent·Most cited

Myosin 10 uses its MyTH4 and FERM domains differentially to support two aspects of spindle pole biology required for mitotic spindle bipolarity

Y.-I. Yim, A. Pedrosa, X. Wu, K. Chinthalapudi, R. E. Cheney, J. Hammer

This study shows Myo10's MyTH4 and FERM domains differentially support spindle pole integrity and supernumerary centrosome clustering, maintaining mitotic spindle bipolarity.

bioRxiv · Jun 15, 2023 · PreprintCell Biology

Competition between myosin II and βH-Spectrin regulates cytoskeletal tension

C. Ibar, K. Chinthalapudi, S. Heissler, K. D. Irvine

The paper investigates how βH-Spectrin and myosin II compete for binding to apical F-actin, regulating cytoskeletal tension and Hippo signaling in Drosophila wing imaginal discs.

bioRxiv · Dec 1, 2022Cell Biology

Structural Mechanisms of Actin Isoforms

A. S. Arora, H.-L. Huang, R. Singh, Y. Narui, T. Hatano, S. Heissler, M. K. Balasubramanian, K. Chinthalapudi, A. Suchenko

The paper reports high-resolution structures of actin isoforms with native PTMs, revealing isoform-specific conformations and their functional implications.

bioRxiv · Aug 1, 2022Biochemistry

Mechanistic Insights Into The Active Site And Allosteric Communication Pathways In Human Nonmuscle Myosin-2C

K. Chinthalapudi, S. M. Heissler, M. Preller, J. R. Sellers, D. J. Manstein

This study presents a crystal structure of human nonmuscle myosin-2C and identifies an allosteric communication pathway that affects nucleotide binding and release kinetics.

bioRxiv · May 17, 2017Biochemistry