Author

K. Chrzastek

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Immunology· 2

Signature Assays, Organisms & Methods

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Organism:chicken / avian· 5 Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Assay:metagenomics· 2 Approach:statistical model· 2 Research Focus:development & morphogenesis· 1 Research Focus:genome assembly· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

D. Bialy· 3 shared D. Kapczynski· 3 shared H. Shelton· 3 shared K. Segovia· 3 shared J. Leng· 2 shared J. Mo· 2 shared R. La Ragione· 2 shared C. Conceicao· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersMicrobiology

D. Bialy

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Genetic insertion of mouse Myxovirus-resistance gene 1 increases innate resistance against both high and low pathogenic avian influenza virus by significantly decreasing replication in chicken DF1 cell line

K. R. Briggs, K. Chrzastek, K. Segovia, J. Mo, D. Kapczynski

This study introduces mouse Mx1 into chicken cells to enhance resistance against avian influenza, showing reduced viral replication and cytopathic effects.

bioRxiv · Feb 12, 2024Immunology

Morphologic characterization and cytokine response of chicken bone-marrow derived dendritic cells to infection with high and low pathogenic avian influenza virus

J. Mo, K. Segovia, K. Chrzastek, K. Briggs, D. Kapczynski

This study examines the morphological changes and cytokine response of chicken bone-marrow derived dendritic cells infected with high and low pathogenic avian influenza viruses.

bioRxiv · Feb 6, 2024Immunology

Alteration of the chicken upper respiratory microbiota following H9N2 avian influenza virus infection

T. Davis, D. Bialy, J. Leng, R. La Ragione, H. Shelton, K. Chrzastek

This study examines how H9N2 avian influenza virus infection affects the upper respiratory microbiota diversity and composition in chickens, finding reduced alpha diversity and persistent microbiota changes during recovery.

bioRxiv · Aug 8, 2023 · PreprintMicrobiology

Novel technology to develop non-transmissible live influenza virus vaccines through alterations in M2/M42 ion channel expression

D. Kapczynski, K. Segovia, K. Chrzastek, C. Conceicao, D. L. Suarez, L. Vervelde, P. Digard

This paper develops non-transmissible live influenza virus vaccines by altering M2/M42 ion channel expression, showing they protect against H5 HPAIV without transmission.

bioRxiv · Apr 11, 2023 · PreprintMicrobiology

A random priming amplification method for whole genome sequencing of SARS-CoV-2 and H1N1 influenza A virus.

K. Chrzastek, C. Tennakoon, D. Bialy, G. L. Freimanis, J. Flannery, H. Shelton

This paper compares random priming amplification methods for whole genome sequencing of SARS-CoV-2 and H1N1 influenza A virus, finding that the SISPA method is most effective for non-targeted sequencing.

bioRxiv · Jun 25, 2021 · PreprintMicrobiology

Low pathogenic avian influenza virus infection retards colon microbiome diversification in two different chicken lines

K. Chrzastek, J. Leng, M. K. Zakaria, D. Bialy, R. La Ragione, H. Shelton

This study shows that low pathogenic avian influenza virus infection reduces colon microbiome diversity in two chicken breeds, delaying its recovery.

bioRxiv · Mar 15, 2021Microbiology