Author

T. Jamieson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Hedley· 2 shared F. Fercoq· 2 shared G. J. Graham· 2 shared J. B. G. Mackey· 2 shared K. Gilroy· 2 shared O. J. Sansom· 2 shared X. Cortes-Lavaud· 2 shared A. Collins· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersCancer Biology

A. Hedley

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

CXCR2 inhibition enables NASH-HCC immunotherapy

J. Leslie, J. B. G. Mackey, T. Jamieson, E. Ramon-Gil, T. M. Drake, F. Fercoq, W. Clark, K. Gilroy, A. Hedley, C. Nixon, S. Luli, M. Laszczewska, R. Pinyol, R. Esteban-Fabro, C. E. Willoughby, , Carlin

This study shows that combining CXCR2 inhibition with anti-PD1 therapy enhances immunotherapy response in NASH-HCC by reprogramming tumor-associated neutrophils.

bioRxiv · Feb 24, 2022Cancer Biology

Maturation, developmental site, and pathology dictate murine neutrophil function

J. B. G. Mackey, A. J. McFarlane, T. Jamieson, R. Jackstadt, X. L. Raffo-Iraolagoitia, J. Secklehner, X. Cortes-Lavaud, F. Fercoq, W. Clarke, A. Hedley, K. Gilroy, S. Lilla, J. Vuononvirta, G. J. Graham, K. De Filippo, , L. M. Carlin

This study identifies Ly6G expression levels as a marker for neutrophil maturation stages and shows spleen-derived neutrophils mature faster with distinct transcriptional profiles.

bioRxiv · Jul 21, 2021 · PreprintImmunology

Characterization of Critical Determinants of ACE2-RBD Interaction

E. E. F. Brown, R. Rezaei, T. Jamieson, J. Dave, N. T. Martin, R. Singaravelu, M. J. F. Crupi, S. Boulton, S. Tucker, J. Duong, J. Poutou, A. Pelin, H. Yasavoli-Sharahi, Z. Taha, R. Arulanandam, , T. Azad

This study identifies critical amino acid residues in SARS-CoV-2 RBD and ACE2 that influence binding affinity and neutralization by antibodies and inhibitors.

bioRxiv · Jan 29, 2021 · PreprintMicrobiology

Aspirin-mediated DKK-1 increase rescues Wnt-driven stem-like phenotype in human intestinal organoids

K. Dunbar, A. Valanciute, V. Rajasekaran, T. Jamieson, P. Freile Vinuela, A. Lima, J. Blackmur, A.-M. Ochocka-Fox, M. J. Arends, O. J. Sansom, K. B. Myant, S. M. Farrington, M. G. Dunlop, F. V. N. Din

The paper shows aspirin reduces Wnt-driven stem-like traits in intestinal organoids by increasing DKK-1, suggesting a mechanism for its anti-cancer effects.

bioRxiv · Oct 17, 2019 · PreprintCancer Biology