Author

K. E. Carothers

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Organism:C. elegans· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

D. E. Hammers· 2 shared F. R. Fields· 2 shared G. Vedantam· 2 shared J. N. Ross· 2 shared S. W. Lee· 2 shared V. Viswanathan· 2 shared A. D. Hildreth· 1 shared A. E. Clark· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMicrobiology

D. E. Hammers

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A superoxide reductase contributes to Clostridioides difficile resistance to oxygen

R. Kochanowsky, K. E. Carothers, B. Roxas, F. Anwar, V. Viswanathan, G. Vedantam

This study identifies a superoxide reductase (SOR) in C. difficile that contributes to its resistance to oxygen and oxidative stress.

bioRxiv · Dec 19, 2022 · PreprintMicrobiology

The Alternative Sigma Factor SigL Influences Clostridioides difficile Toxin Production, Sporulation, and Cell Surface Properties

A. E. Clark, C. C. Adamson, K. E. Carothers, B. A. P. Roxas, V. Viswanathan, G. Vedantam

This study shows that SigL, an alternative sigma factor in C. difficile, affects toxin production, sporulation, and cell surface properties differently in two strains.

bioRxiv · Jan 26, 2022Microbiology

Discovery of genes encoding a Streptolysin S-like toxin biosynthetic cluster in a select highly pathogenic methicillin resistant Staphylococcus aureus JKD6159 strain

T. Kane, K. E. Carothers, Y. Bao, W.-S. Yeo, T. Bae, C. Park, F. R. Fields, H. M. Vu, D. E. Hammers, J. N. Ross, V. A. Ploplis, F. J. Castellino, S. W. Lee

The paper identifies a Streptolysin S-like toxin biosynthetic cluster in a highly pathogenic MRSA strain and investigates its potential role through genetic and phenotypic assays.

bioRxiv · Aug 31, 2019 · PreprintMicrobiology

Novel antimicrobial peptide discovery using machine learning and biophysical selection of minimal bacteriocin domains

F. R. Fields, S. D. Freed, K. E. Carothers, M. N. Hamid, D. E. Hammers, J. N. Ross, V. R. Kalwajtys, A. J. Gonzalez, A. D. Hildreth, I. Friedberg, S. W. Lee

This study develops a pipeline combining machine learning and biophysical filters to design and test minimal bacteriocin peptides for antimicrobial activity.

bioRxiv · May 4, 2018Microbiology