Author

K. F. Harvey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. Kulkarni· 1 shared B. Kroeger· 1 shared B. L. Parker· 1 shared G. Ramm· 1 shared J. H. A. Vissers· 1 shared J. Rosenbluh· 1 shared L. Post· 1 shared M. Manning· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. Kulkarni

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2 papers

Recent·Most cited

Basal spot junctions of epithelial tissues respond to morphogenetic forces and regulate Hippo signalling

B. Kroeger, S. A. Manning, Y. Fonseka, V. Oorschot, S. A. Crawford, G. Ramm, K. F. Harvey

The paper identifies basal spot junctions in Drosophila epithelial tissues that respond to mechanical forces and regulate Hippo signaling by sequestering Warts kinase.

bioRxiv · Sep 17, 2023 · PreprintCell Biology

Identification of resistance mechanisms to small-molecule inhibition of TEAD-regulated transcription

A. Kulkarni, V. Mohan, T. Tang, L. Post, M. Manning, N. Thio, B. L. Parker, J. Rosenbluh, J. H. A. Vissers, K. F. Harvey

This study identifies resistance mechanisms to TEAD inhibitors by showing MAPK hyperactivation can counteract their effects and suggests combining TEAD and MEK inhibition as a therapeutic strategy.

bioRxiv · Aug 16, 2023Cancer Biology