Author

V. Oorschot

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 6 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 4 Assay:imaging· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:clustering· 2 Research Focus:development & morphogenesis· 2 Assay:fluorescence / live-cell microscopy· 2 Organism:human· 2

Frequent Co-Authors

A. Halavatyi· 2 shared G. Ramm· 2 shared A. Carter· 1 shared A. de Marco· 1 shared A. Handley· 1 shared A. I. Isiaku· 1 shared A. J. Wood· 1 shared A. M. Khan· 1 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 6 mutual co-author links

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2 shared papersCell Biology

A. Halavatyi

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Basal spot junctions of epithelial tissues respond to morphogenetic forces and regulate Hippo signalling

B. Kroeger, S. A. Manning, Y. Fonseka, V. Oorschot, S. A. Crawford, G. Ramm, K. F. Harvey

The paper identifies basal spot junctions in Drosophila epithelial tissues that respond to mechanical forces and regulate Hippo signaling by sequestering Warts kinase.

bioRxiv · Sep 17, 2023 · PreprintCell Biology

Dextromethorphan inhibits collagen transport in the endoplasmic reticulum eliciting an anti-fibrotic response in ex-vivo and in vitro models of pulmonary fibrosis

M. M. Khan, J. Zukowska, J. Jung, G. Galea, N. Tuechler, A. Halavatyi, C. Tischer, P. Haberkant, F. Stein, F. Jung, J. Landry, A. M. Khan, V. Oorschot, I. Becher, B. Neumann, , R. Pepperkok

This study shows Dextromethorphan reduces collagen deposition in fibrotic models by inhibiting collagen trafficking in the endoplasmic reticulum.

bioRxiv · Apr 19, 2023 · PreprintCell Biology

Targeted volume Correlative Light and Electron Microscopy of an environmental marine microorganism

K. Mocaer, G. Mizzon, M. Gunkel, A. Halavatyi, A. M. Steyer, V. Oorschot, M. Schorb, C. Le Kieffre, D. P. Yee, F. Chevalier, B. Gallet, J. Decelle, Y. Schwab, P. Ronchi

The paper demonstrates a method to target and analyze the 3D ultrastructure of a photosynthetic marine microorganism using correlative light and electron microscopy.

bioRxiv · Jan 27, 2023Cell Biology

Fibre-specific mitochondrial protein abundance is linked to resting and post-training mitochondrial content in human muscle.

E. Reisman, J. Botella Ruiz, C. Huang, R. B. Schittenhelm, D. A. Stroud, C. Granata, S. Chandrasiri, G. Ramm, V. Oorschot, N. J. Caruana, D. J. Bishop

The paper examines fibre-specific mitochondrial protein abundance in human muscle before and after training, finding that most differences are linked to mitochondrial content rather than fibre-type-specific remodelling.

bioRxiv · Oct 23, 2022 · PreprintPhysiology

Bimodal Endocytic Probe for Three-Dimensional Correlative Light and Electron Microscopy

J. Fermie, L. de Jager, H. Foster, T. Veenendaal, C. de Heus, S. van Dijk, C. ten Brink, V. Oorschot, L. Yang, W. Li, W. Muller, S. Howes, A. Carter, F. Foerster, G. Posthuma, , N. Liv

This paper introduces fBSA-Au, a bimodal endocytic tracer for 2D and 3D CLEM, enabling accurate registration of fluorescence to EM data with sub-200 nm precision.

bioRxiv · May 18, 2021Cell Biology

Macrophages provide a transient muscle stem cell niche via NAMPT secretion

D. Ratnayake, P. D. Nguyen, F. J. Rossello, V. C. Wimmer, A. I. Isiaku, L. A. Galvis, A. J. Wood, Z. Julier, T. Boudier, V. Oorschot, K. L. Rogers, M. M. Martino, C. Marcelle, G. J. Lieschke, J. Bakkers, P. D. Currie

The paper identifies macrophages as a transient niche for muscle stem cells through NAMPT secretion, which activates CCR5 on stem cells to drive muscle regeneration.

bioRxiv · Aug 24, 2020Cell Biology

Oxygen plasma focused ion beam scanning electron microscopy for biological samples

S. Gorelick, D. Korneev, A. Handley, G. Gervinskas, V. Oorschot, O. L. Kaluza, R. H. Law, M. O'Bryan, R. Pocock, J. C. Whisstock, A. de Marco

This paper introduces oxygen plasma FIB-SEM as a faster and more versatile method for cellular tomography compared to gallium FIB-SEM.

bioRxiv · Oct 31, 2018 · PreprintCell Biology