C. K. E. Bleck

Mitochondrial Network Configuration Influences Sarcomere and Myosin Filament Structure in Striated Muscles

The paper shows mitochondrial network configuration affects sarcomere and myosin filament structure in striated muscles across species.

OMA1 mediates local and global stress responses against protein misfolding in CHCHD10 mitochondrial myopathy

Regulation of the Evolutionarily Conserved Muscle Myofibrillar Matrix by Cell Type Dependent and Independent Mechanisms

The paper shows that a myofibrillar matrix is conserved across species and regulated by both cell-type dependent and independent mechanisms in Drosophila muscles.

An Evolutionarily Conserved Regulatory Pathway of Muscle Mitochondrial Network Organization

The paper identifies an evolutionarily conserved pathway involving cut, salm, and H15 that regulates muscle mitochondrial network organization independently of contractile fiber-type in Drosophila.

Orchestrated Restructuring Events During Secretory Granule Maturation Mediate Intragranular Cargo Segregation

This study identifies intragranular restructuring events during secretory granule maturation that mediate cargo segregation and reveals genes and factors involved in these processes.

A comprehensive approach for artifact-free sample preparation and assessment of mitochondrial morphology in tissue and cultured cells

This paper presents a method for preserving and quantitatively measuring mitochondrial morphology in tissues and cultured cells without introducing artifacts.

Reorganization of the Mitochondria-Organelle Interactome during Postnatal Development in Skeletal Muscle

This study shows how mitochondrial-organelle interactions reorganize during skeletal muscle development, shifting from inter-organelle communication to contractile specialization.

Metabolic design in a model of extreme mammalian metabolism, the North American least shrew (Cryptotis parva)

The paper examines mitochondrial structure and function in the least shrew, revealing organ-specific adaptations in mitochondrial networks and protein composition related to metabolic demand.

Kinesin-1 motility traced by an activity-based precipitating dye

This study develops a fluorogenic substrate that visualizes kinesin-1 motility in live cells by producing a precipitating dye along its transport path.

LRRK2 mediates tubulation and vesicle sorting from membrane damaged lysosomes

This study identifies LRRK2's role in lysosomal tubulation and vesicle sorting from damaged lysosomes, introducing the process LYTL.

Proteotype profiling unmasks a viral signaling network essential for poxvirus assembly and transcriptional competence

The paper identifies a viral signaling network regulated by F10 kinase and H1 phosphatase through phosphoproteomic analysis, revealing their roles in poxvirus assembly and transcriptional competence.