Author

K. Gottimukkala

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 5 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 2

Frequent Co-Authors

A. Chandele· 5 shared E. S. Reddy· 5 shared C. W. Davis· 4 shared K. Murali-Krishna· 4 shared K. Nayak· 4 shared R. Ahmed· 4 shared S. Kumar· 4 shared A. Sharma· 3 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersImmunology

A. Chandele

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Author profile →

5 papers

Recent·Most cited

Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response

A. Patel, S. Kumar, L. Lai, C. Chakravarthy, R. Valanparambil, E. S. Reddy, K. Gottimukkala, P. Bajpai, D. R. Raju, V. V. Edara, M. E. Davis-Gardner, S. Linderman, K. Dixit, P. Sharma, G. Mantus, , E. A. Ortlund

The paper identifies three monoclonal antibodies that poorly neutralize the Omicron BA.1 variant, revealing structural and molecular features of antibody evasion.

bioRxiv · Oct 24, 2022Immunology

Transcriptional profiles of functionally distinct HLADR+CD38+ CD8 T cells subsets from acute febrile dengue patients

P. Singh, P. Bajpai, D. Maheshwari, Y. M. Chawla, K. Gottimukkala, E. S. Reddy, K. Saini, K. Nayak, S. Gunisetty, C. Aggarwal, S. Jain, C. Verma, P. Jain, M. Soneja, N. Wig, , A. Chandele

This study identifies transcriptional differences among HLADR+CD38+ CD8 T cell subsets in dengue patients and shows similar expansion patterns across disease severity grades.

bioRxiv · Sep 9, 2022 · PreprintImmunology

Structural insights for neutralization of BA.1 and BA.2 Omicron variants by a broadly neutralizing SARS-CoV-2 antibody

S. Kumar, A. Patel, L. Lai, C. Chakravarthy, R. Valanparambil, M. E. Davis-Gardner, V. V. Edara, S. Linderman, E. S. Reddy, K. Gottimukkala, K. Nayak, P. Bajpai, V. Singh, F. Frank, N. Cheedarla, , A. Chandele

This paper identifies and structurally analyzes an antibody that neutralizes SARS-CoV-2 BA.1 and BA.2 variants, revealing its unique epitope and mechanism of action.

bioRxiv · May 13, 2022Immunology

Immunophenotyping and transcriptional profiling of human plasmablasts in dengue.

C. Aggarwal, K. Saini, E. S. Reddy, M. Singla, K. Nayak, Y. Chawla, D. Maheshwari, P. Singh, P. Sharma, P. Bhatnagar, S. Kumar, K. Gottimukkala, H. Panda, S. Gunisetty, C. W. Davis, , A. Chandele

This study characterizes plasmablasts in dengue patients from India, showing their transcriptional features, adhesion molecule expression, and differential expansion based on infection severity.

bioRxiv · Apr 9, 2021Immunology

Characterization of neutralizing versus binding antibodies and memory B cells in COVID-19 recovered individuals from India

K. Nayak, K. Gottimukkala, S. Kumar, E. S. Reddy, V. V. Edara, R. Kauffman, K. Floyd, G. Mantus, D. Savargaonkar, P. K. Goel, S. Arora, M. Rahi, C. W. Davis, S. Linderman, J. Wrammert, , A. Chandele

This study examines humoral and memory B cell responses in Indian COVID-19 recovered individuals, finding that RBD-specific IgG correlates with neutralizing antibodies and can serve as a surrogate for neutralization assays.

bioRxiv · Aug 31, 2020Immunology