C. Verma

Modulation of Ideonella sakaiensis PETase active site flexibility and activity on morphologically distinct substrates by surface charge engineering

The paper investigates how surface charge mutations affect PETase activity on different PET substrates and identifies an engineered variant with improved degradation efficiency.

Reproductive traits of the European catfish (Silurus glanis) during the early stages of invasion in the Lower Tagus River

This study examines reproductive traits of non-native European catfish in the Lower Tagus River, finding variations in maturity size, spawning season, and fecundity influenced by environmental factors.

Expanding the DNA editing toolbox: novel lambda integrase variants targeting microalgal and human genome sequences.

This paper describes the directed evolution of lambda integrase variants that target microalgal and human genome sequences, showing enhanced specificity for non-natural sites.

Transcriptional profiles of functionally distinct HLADR+CD38+ CD8 T cells subsets from acute febrile dengue patients

This study identifies transcriptional differences among HLADR+CD38+ CD8 T cell subsets in dengue patients and shows similar expansion patterns across disease severity grades.

Dual scRNA-Seq analysis reveals rare and uncommon parasitized cell populations in chronic L. donovani infection

This study uses dual scRNA-seq to identify rare parasitized cell populations in L. donovani infection, revealing HSCs as dominant in bone marrow and new infected cell types in spleen.

Discovery of cell active macrocyclic peptides with on-target inhibition of KRAS signaling

This paper identifies macrocyclic peptides that inhibit KRAS signaling by binding to its hydrophobic pocket, showing on-target activity and improved proteolytic stability.

Phosphorylation regulates auto-inhibition of kinesin KIF3A

This study identifies phosphorylation of serine-689/690 in KIF3A as critical for relieving auto-inhibition through conformational changes in the motor-tail interaction.