K. Jahnke

Self-assembly and contraction of micron-scale DNA rings

This paper describes the creation of DNA-based contractile rings that can contract through two mechanisms, expanding DNA nanotechnology applications.

A DNA segregation module for synthetic cells

This paper develops an entropy-driven DNA segregation module using DNA Y-motifs in synthetic cells, showing controlled segregation via cleavage and environmental factors.

Mechanochemical signal transduction in synthetic cells

This study designs DNA origami signaling units that mechanically couple to DNA cytoskeletons in synthetic cells, enabling both chemical and mechanical transmembrane signaling.

Simultaneous adjustments of major mitochondrial pathways through redox regulation of dihydrolipoamide dehydrogenase (mtLPD1)

The paper shows redox regulation of mtLPD1 modulates photorespiration, TCA-cycle, and BCAA degradation in response to environmental changes.

Triosephosphate export from chloroplasts regulates flavonoid biosynthesis and permits high light acclimation through the inactivation of SnRK1

This study shows that triosephosphate export from chloroplasts activates flavonoid biosynthesis during high light acclimation by inactivating SnRK1.

Tuning epithelial cell-cell adhesion and collective dynamics with functional DNA-E-cadherin hybrid linkers

This study uses DNA-E-cadherin hybrid linkers to modulate cell-cell adhesion strength and assess its impact on signaling and collective dynamics.

Choice of fluorophore affects dynamic DNA nanostructures

This study shows that fluorophore choice can alter DNA nanostructure dynamics without changing DNA sequences, using experiments, MD simulations, and reaction-diffusion modeling.

An integrated microfluidic platform for quantifying drug permeation across biomimetic vesicle membranes

The paper develops a microfluidic platform to measure drug permeability across biomimetic liposome membranes, demonstrating improved control and yield compared to existing methods.