Author

J. Cama

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 4 Microbiology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:drug response / drug discovery· 3 Organism:E. coli· 2 Research Focus:host-pathogen & immune response· 2 Approach:microscopy & imaging analysis· 2 Research Focus:cell signaling & trafficking· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

U. F. Keyser· 6 shared K. Al Nahas· 4 shared D. Sobota· 2 shared K. Hammond· 2 shared M. Fletcher· 2 shared M. G. Ryadnov· 2 shared M. Schaich· 2 shared S. Pagliara· 2 shared

Activity by Year

2018-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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6 shared papersBiophysics

U. F. Keyser

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

An ultrasensitive microfluidic approach reveals correlations between the physico-chemical and biological activity of experimental peptide antibiotics

J. Cama, K. Al Nahas, M. Fletcher, K. Hammond, M. G. Ryadnov, U. F. Keyser, S. Pagliara

This study uses microfluidic platforms to show strong correlations between peptide antibiotics' physicochemical membrane activity and their cellular biological activity.

bioRxiv · Sep 8, 2021Microbiology

Conformable and robust force sensors to enable precision joint replacement surgery

L. Ives, A. Pace, F. Bor, Q. Jing, T. Wade, J. Cama, V. Khanduja, S. Kar-Narayan

This paper develops a conformable microfluidic force sensor for hip replacement surgery to improve implant longevity by providing quantitative force feedback during procedures.

bioRxiv · Aug 19, 2021 · PreprintBioengineering

Measuring thousands of single vesicle leakage events reveals the mode of action of antimicrobial peptides

K. Al Nahas, M. Fletcher, K. Hammond, C. Nehls, J. Cama, M. G. Ryadnov, U. F. Keyser

The paper uses high-resolution microscopy to study antimicrobial peptides' effects on vesicles, revealing their modes of action through detailed disruption measurements.

bioRxiv · Aug 13, 2021Biophysics

Antibiotic transport kinetics in Gram-negative bacteria revealed via single-cell uptake analysis and mathematical modelling

J. Cama, M. Voliotis, J. Metz, A. Smith, J. Iannucci, U. F. Keyser, K. Tsaneva-Atanasova, S. Pagliara

This study quantifies antibiotic uptake in E. coli using microfluidics and microscopy, showing growth phase impacts drug accumulation more than transport pathways, and develops a mathematical model to predict kinetics.

bioRxiv · Dec 6, 2019Biophysics

Biophysical characterization reveals the similarities of liposomes produced using microfluidics and electroformation

M. Schaich, D. Sobota, H. Sleath, J. Cama, U. F. Keyser

The paper compares biophysical properties of GUVs produced by microfluidics and electroformation, finding similar lateral diffusion coefficients.

bioRxiv · Nov 28, 2019Biophysics

An integrated microfluidic platform for quantifying drug permeation across biomimetic vesicle membranes

M. Schaich, J. Cama, K. Al Nahas, D. Sobota, K. Jahnke, S. Deshpande, C. Dekker, U. F. Keyser

The paper develops a microfluidic platform to measure drug permeability across biomimetic liposome membranes, demonstrating improved control and yield compared to existing methods.

bioRxiv · Jan 17, 2019Biophysics

Indole Pulse Signalling Regulates the Cytoplasmic pH of E. coli in a Memory-Like Manner

A. Zarkan, S. Cano-Muniz, J. Zhu, K. Al Nahas, J. Cama, U. F. Keyser, D. K. Summers

This study shows that indole pulses in E. coli regulate cytoplasmic pH in a memory-like manner, maintaining pH at 7.2 during stationary phase and protecting against stress.

bioRxiv · Sep 24, 2018Microbiology