Receptor for Hyaluronan-Mediated Motility (RHAMM) defines an invasive niche associated with tumor progression and predicts poor outcomes in breast cancer patients.
S. E. Tarullo, Y. He, C. Daughters, T. P. Knutson, C. Henzler, M. Price, R. Shanley, P. Witschen, C. Tolg, R. E. Kaspar, C. Hallstrom, L. Gittsovich, M. L. Sulciner, X. Zhang, C. Forester, , A. C. Nelson
This study identifies RHAMM as a marker of invasive niches in breast cancer, showing its association with poor outcomes and promoting invasion through a 27-gene signature.
bioRxiv · Jun 13, 2022Cancer Biology