K. M. McBride

UNG-RPA interaction governs the choice between high-fidelity and mutagenic uracil repair

The paper identifies the UNG-RPA interaction as determining whether uracil repair is high-fidelity or mutagenic in B cells.

Uracil-DNA Glycosylase of Murine Gammaherpesvirus 68 Binds Cognate Viral Replication Factors Independently of its Catalytic Residues

This paper identifies a non-enzymatic role for murine gammaherpesvirus 68 vUNG in forming a complex with viral DNA replication factors, independent of its catalytic activity.

B cell-intrinsic STAT3-mediated support of latency and interferon suppression during murine gammaherpesvirus 68 infection revealed through an in vivo competition model

This study shows that B cell-intrinsic STAT3 supports gammaherpesvirus latency and suppresses interferon responses in mice, using a competitive infection model.

Characterization of a mouse model of ICF syndrome reveals enhanced CD19 activation in inducing hypogammaglobulinemia

This study characterizes a mouse model of ICF syndrome, revealing that Zbtb24 deficiency leads to hypogammaglobulinemia via enhanced CD19 activation and IL-5 signaling.

The Longitudinal Analysis of Convergent Antibody VDJ Regions in SARS-CoV-2 Positive Patients Using RNA-seq

This study analyzes longitudinal RNA-seq data from SARS-CoV-2 positive and negative patients to identify convergent antibody VDJ sequences and their antigenic specificity across pandemic stages.