Author

K. McDonald

University of British Columbia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Plant Biology· 2 Biophysics· 1 Evolutionary Biology· 1 Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:development & morphogenesis· 2 Organism:plant (other)· 2 Assay:proteomics· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

P. Burkhardt· 2 shared S. Nandi· 2 shared A. Gillen· 1 shared A. J. Behrmann· 1 shared A. J. Turlo· 1 shared A. Varma· 1 shared Allison GacadiD· 1 shared B. Larson· 1 shared

Activity by Year

2018-2025 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 4 mutual co-author links

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2 shared papersCell Biology

P. Burkhardt

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Predicting bacterial-mediated entomopathogenicity through comparative genomics and statistical modeling

Daniela L. Yanez Ortuno, Melissa Y. Chen, K. McDonald, Allison Gacad, Juli Carrillo, Cara H. Haney

This study predicts bacterial genes involved in insect-killing using comparative genomics and statistical models, validated by testing Pseudomonas strains against Drosophila.

Microbiology Spectrum · Nov 26, 2025Peer-reviewedMicrobiology

Combined Right Ventricular Preload and Afterload Challenge Induces Contractile Dysfunction and Ventricular Arrhythmia in an Age-dependent Manner in Isolated Hearts of Dystrophin-deficient Mice

A. J. Behrmann, J. Cayton, M. Hayden, M. Lambert, Z. Nourian, K. Nyanyo, L. Hanft, M. Krenz, K. McDonald, T. L. Domeier

This study shows that dystrophin-deficient mice exhibit age-dependent RV contractile dysfunction and arrhythmia under preload/afterload challenge, with greater damage in middle-aged hearts.

bioRxiv · Nov 14, 2023 · PreprintPhysiology

Four-dimensional quantitative analysis of cell plate development using lattice light sheet microscopy identifies robust transition points between growth phases

R. M. Sinclair, M. Wang, M. Z. Jawaid, J. Aaron, B. Rossetti, E. Wait, K. McDonald, D. Cox, J. heddleston, T. Wilkop, G. Drakakaki

This study uses lattice light sheet microscopy to analyze cell plate development in four dimensions, identifying phase transitions and the role of callose in cytokinesis.

bioRxiv · Oct 3, 2023 · PreprintPlant Biology

Evolution of the ribbon-like organization of the Golgi apparatus in animal cells

G. Benvenuto, S. Leone, E. Astoricchio, S. Bormke, S. Jasek, E. D'Aniello, M. Kittelmann, K. McDonald, V. Hartenstein, V. Baena, H. Escriva, S. Bertrand, B. Schierwater, P. Burkhardt, I. Ruiz-Trillo, , F. Ferraro

This study investigates the evolutionary origin of the Golgi ribbon in animal cells, identifies a molecular mechanism for its formation, and suggests its role in development.

bioRxiv · Feb 16, 2023Cell Biology

Mesenchymal Stromal Cell secretome is affected by tissue source, donor age and sex.

A. J. Turlo, D. E. Hammond, K. A. Ramsbottom, J. Soul, A. Gillen, K. McDonald, M. J. Peffers, P. D. Clegg

This study identifies how donor age, sex, and tissue source affect the protein composition of equine mesenchymal stromal cell secretomes, with age showing the strongest impact.

bioRxiv · Jan 30, 2023Cell Biology

SARS-Cov-2 Spike binding to ACE2 is stronger and longer ranged due to glycan interaction

Y. Huang, B. S. Harris, S. A. Minami, S. Jung, P. Shah, S. Nandi, K. McDonald, R. Faller

The paper uses molecular dynamics simulations to show that glycosylation enhances the binding strength and range of SARS-CoV-2 Spike to ACE2 through glycan-mediated interactions.

bioRxiv · Jul 15, 2021Biophysics

Bioprinting transgenic plant cells for production of a recombinant biodefense agent

A. Varma, H. B. Gemeda, M. J. McNulty, K. McDonald, S. Nandi, J. Knipe

The paper demonstrates a bioprinting system using transgenic rice cells to produce recombinant BChE, maintaining viability and production levels comparable to liquid cultures.

bioRxiv · Feb 1, 2021Plant Biology

The architecture of cell differentiation in choanoflagellates and sponge choanocytes

D. Laundon, B. Larson, K. McDonald, N. King, P. Burkhardt

This study compares the subcellular architecture of solitary and colonial choanoflagellate cells with sponge choanocytes to uncover the architecture of cell differentiation in these ancient cell types.

bioRxiv · Oct 29, 2018Evolutionary Biology