I. Ruiz-Trillo

Evolution of promoter-proximal pausing enabled a new layer of transcription control

The paper investigates the evolutionary emergence of RNA polymerase II pausing and its regulatory role across species.

Evolution of the ribbon-like organization of the Golgi apparatus in animal cells

This study investigates the evolutionary origin of the Golgi ribbon in animal cells, identifies a molecular mechanism for its formation, and suggests its role in development.

Chemical factors induce aggregative multicellularity in a close unicellular relative of animals

The paper shows that chemical cues induce reversible multicellularity in Capsaspora owczarzaki, a unicellular relative of animals, suggesting this mechanism was present in ancestral unicellular life.

Taxonomic composition, community structure and molecular novelty of microeukaryotes in a temperate oligomesotrophic lake as revealed by metabarcoding

The paper uses metabarcoding to analyze microeukaryote diversity in Sanabria Lake, revealing new molecular data and community structures in different habitats.

Evolutionary analysis of p38 stress-activated kinases in unicellular relatives of animals suggests an ancestral function in osmotic stress

This study investigates the evolutionary origin and diversification of p38 kinases in animals and fungi, showing their ancestral role in osmotic stress response and subsequent functional expansion in animals.

A phylogenetic and proteomic reconstruction of eukaryotic chromatin evolution

This study reconstructs the evolutionary history of eukaryotic chromatin by combining proteomics and phylogenetic analysis, revealing pre-eukaryotic origins of chromatin functions and eukaryotic innovations.

Poly(A)-binding protein is an ataxin-2 chaperone that emulsifies biomolecular condensates.

The paper identifies a conserved 14aa sequence in ataxin-2 that acts as a condensation switch and reveals poly(A)-binding proteins as RNA-dependent chaperones that regulate this switch.

Regulation of sedimentation rate shapes the evolution of multicellularity in a unicellular relative of animals.

This study shows that sedimentation rate varies widely among Sphaeroforma species and can evolve through cellular mechanisms like clumping and nuclear doubling, influencing multicellularity.

Txikispora philomaios n. sp., n. g., a Micro-Eukaryotic Pathogen of Amphipods, Reveals Parasitism and Hidden Diversity in Class Filasterea

This study identifies a new parasitic micro-eukaryote in amphipods, describes its morphology and phylogeny, and expands known Filasterea diversity through environmental metagenomics.

Integrin-mediated adhesion in the unicellular holozoan Capsaspora owczarzaki

This study shows that the unicellular holozoan Capsaspora owczarzaki uses integrins for cell-substrate adhesion, suggesting integrin-mediated adhesion predates animals.

On the origin and evolution of RNA editing in metazoans

The paper investigates the origin and evolution of A-to-I RNA editing in metazoans, finding it emerged in the common ancestor and is nonadaptive in most regions except for specific taxa.

A unicellular relative of animals generates an epithelium-like cell layer by actomyosin-dependent cellularization

The paper studies cellularization in Sphaeroforma arctica, showing it forms an epithelium-like layer via actomyosin-dependent membrane invaginations and regulated gene activation.

Reticulate evolution in eukaryotes: origin and evolution of the nitrate assimilation pathway

The paper investigates the evolution of the eukaryotic nitrate assimilation pathway, revealing multiple horizontal gene transfers and gene fusions across diverse lineages.

Metabarcoding analysis on European coastal samples reveals new molecular metazoan diversity

The paper uses metabarcoding to analyze European coastal samples, revealing high molecular diversity and novel taxa in marine environments.

Decoupling of the nuclear division cycle and cell size control in the coenocytic cycle of the ichthyosporean Sphaeroforma arctica

This study shows that Sphaeroforma arctica maintains regular nuclear division cycles regardless of nutrient levels, while cell size adjusts to nutrient availability.