F. A. Hussain

Prevotella are major contributors of sialidases in the human vaginal microbiome.

This study identifies Prevotella as a major source of sialidases in the vaginal microbiome, showing their prevalence and activity compared to Gardnerella.

Vaginal Lactobacillus fatty acid response mechanisms reveal a novel strategy for bacterial vaginosis treatment

This study identifies oleic acid as a compound that inhibits L. iners and promotes L. crispatus growth, offering a potential new treatment strategy for bacterial vaginosis.

Small protein modules dictate prophage fates during polylysogeny

The paper identifies small protein modules in phages that independently control prophage induction without relying on DNA damage cues, revealing alternative pathways for lysis in polylysogeny.

Resolving the structure of phage-bacteria interactions in the context of natural diversity

The paper studies phage-bacteria interactions in marine environments, finding sparse killing and common recombination among phages.

Cysteine dependence in Lactobacillus iners constitutes a novel therapeutic target to modify the vaginal microbiota

This study identifies cysteine dependence in Lactobacillus iners as a therapeutic target to shift vaginal microbiota from L. iners-dominant to L. crispatus-dominant states.

Rapid evolutionary turnover of mobile genetic elements drives microbial resistance to viruses

The paper shows that mobile genetic elements rapidly evolve to confer phage resistance in bacteria, with resistance unlinked to other genomic features.