Author

S. H. Gellman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Biophysics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Moscona· 2 shared B. P. Cary· 2 shared F. T. Bovier· 2 shared M. Porotto· 2 shared B. L. Haagmans· 1 shared B. Rockx· 1 shared C. A. Alabi· 1 shared C. Qiu· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersMicrobiology

A. Moscona

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Kinetic and Thermodynamic Insights on Agonist Interactions with the Parathyroid Hormone Receptor-1 from a New NanoBRET assay

Z. Yu, B. P. Cary, T. W. Kim, K. Nguyen, T. J. Gardella, S. H. Gellman

The paper introduces a new NanoBRET assay to study agonist interactions with PTHR1, revealing kinetic and thermodynamic insights into ligand binding and activation.

bioRxiv · Jul 25, 2022Biochemistry

Characterization of Hydrophobic Interactions of SARS-CoV-2 and MERS-CoV Spike Protein Fusion Peptides Using Single Molecule Force Measurements

C. Qiu, G. Whittaker, S. H. Gellman, S. Daniel, N. L. Abbott

This study uses single molecule force measurements to quantify hydrophobic interactions in SARS-CoV-2 and MERS-CoV FP1 sequences, revealing that a single residue difference significantly affects interaction strength.

bioRxiv · Mar 5, 2022 · PreprintBiophysics

Structural and Functional Diversity among Agonist-Bound States of the GLP-1 Receptor

B. P. Cary, P. Zhao, T. T. Truong, S. J. Piper, M. J. Belousoff, R. Danev, P. M. Sexton, D. Wootten, S. H. Gellman

This study investigates how peptide agonist conformational plasticity influences GLP-1R activation through structural and functional analysis.

bioRxiv · Feb 24, 2021Pharmacology & Toxicology

Engineering protease-resistant peptides to inhibit human parainfluenza viral respiratory infection

V. K. Outlaw, R. W. Cheloha, E. Jurgens, F. T. Bovier, Y. Zhu, D. F. Kreitler, O. K. Harder, S. Niewiesk, M. Porotto, S. H. Gellman, A. Moscona

This paper develops protease-resistant lipopeptides to inhibit HPIV3 infection by modifying the HRC domain, showing improved in vivo stability and antiviral activity in animals.

bioRxiv · Feb 22, 2021Microbiology

Intranasal fusion inhibitory lipopeptide prevents direct contact SARS-CoV-2 transmission in ferrets

R. D. de Vries, K. S. Schmitz, F. T. Bovier, D. Noack, B. L. Haagmans, S. Biswas, B. Rockx, S. H. Gellman, C. A. Alabi, R. L. de Swart, A. MOSCONA, M. Porotto

bioRxiv · Nov 4, 2020Microbiology