K. Sadtler

Ectopic adipogenesis in response to injury and material implantation in an autoimmune mouse model

The paper compares adipogenesis and immune responses in MRL/MpJ and C57BL/6 mice after injury and material implantation, finding differences in adipose tissue formation and foreign body reactions.

Conserved and tissue-specific immune responses to biologic scaffold implantation

This study examines immune responses to decellularized extracellular matrix implants in different tissue environments, finding location-specific recruitment of immune cells like macrophages and B cells.

Label-free cleared tissue microscopy and machine learning for 3D histopathology of biomaterial implants

This study uses cleared tissue microscopy and machine learning to analyze 3D histopathology of biomaterial implants and their interaction with tissue microenvironments.

The CD103-XCR1 axis mediates the recruitment of immunoregulatory dendritic cells after traumatic injury

The paper identifies the CD103-XCR1 axis as critical for recruiting immunoregulatory dendritic cells that promote tissue regeneration after traumatic injury.

Improved production of SARS-CoV-2 spike receptor-binding domain (RBD) for serology assays

The paper improves the production of SARS-CoV-2 spike RBD for serology assays by optimizing DNA constructs, purification parameters, and demonstrating the role of a carboxyterminal tag in sensitivity.

Optimizing high-yield production of SARS-CoV-2 soluble spike trimers for serology assays

This study improves the yield of SARS-CoV-2 spike protein for serology assays by optimizing expression and purification parameters, achieving 5 mg/L production.

Interleukin 17 and senescence regulate the foreign body response

This study identifies IL17 and senescence as regulators of the foreign body response, showing their roles in fibrosis and potential as therapeutic targets.