Spatial transcriptomics analysis of neoadjuvant cabozantinib and nivolumab in advanced hepatocellular carcinoma identifies independent mechanisms of resistance and recurrence
S. Zhang, L. Yuan, L. Danilova, G. Mo, Q. Zhu, A. Deshpande, A. T. F. Bell, J. Elisseeff, A. S. Popel, R. A. Anders, E. M. Jaffee, M. Yarchoan, E. J. Fertig, L. T. Kagohara
This study uses spatial transcriptomics to analyze HCC tumors treated with cabozantinib and nivolumab, identifying distinct immune and fibrotic mechanisms linked to response and recurrence.
bioRxiv · Jan 10, 2023Cancer Biology