Author

M. T. Wolf

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. Tam· 2 shared D. M. Pardoll· 2 shared F. Housseau· 2 shared J. I. Andorko· 2 shared A. Bhatta· 1 shared A. Lebid· 1 shared A. Lemoff· 1 shared A. Mageau· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBioengineering

A. Tam

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Engineering Tumor Stroma Morphogenesis Using Dynamic Cell-Matrix Spheroid Assembly

M. J. Buckenmeyer, E. A. Brooks, M. S. Taylor, L. Yang, R. J. Holewinski, T. J. Meyer, M. Galloux, M. Garmendia-Cedillos, T. J. Pohida, T. Andresson, B. St. Croix, M. T. Wolf

This paper develops a 3D self-assembly system to engineer tumor stroma-like structures using decellularized ECM and cancer cells, showing effects on malignancy and metabolism.

bioRxiv · Mar 19, 2024Bioengineering

Insulin receptor substrate 4 deficiency mediates the insulin effect on the epithelial magnesium channel TRPM6 and causes hypomagnesemia

J. Zhang, S. W. An, S. Neelam, A. Bhatta, M. Nie, C. Duran, M. Bal, F. Latta, J. S. Hou, J. J. Otto, J. Kozlitina, A. Lemoff, J. Hoenderop, M. Baum, M. T. Wolf

This paper identifies IRS4 as a novel regulator of TRPM6 channel activity and Mg2+ homeostasis, showing IRS4 mediates insulin's effect on TRPM6 phosphorylation and Mg2+ absorption.

bioRxiv · Oct 1, 2022 · PreprintPhysiology

Transfer learning of an in vivo-derived senescence signature identifies conserved and tissue-specific senescence across species and diverse pathologies

C. Cherry, J. I. Andorko, K. Krishnan, J. C. Mejias, H. H. Nguyen, K. B. Stivers, E. F. Gray-Gaillard, A. Ruta, N. Hamada, M. Hamada, I. Sturmlechner, S. Trewartha, J. H. Michel, L. D. Huyer, M. T. Wolf, , J. H. Elisseeff

The paper develops a transfer learning approach to identify senescent cells across species and tissues using an in vivo-derived gene expression signature, revealing conserved and tissue-specific senescence features.

bioRxiv · Mar 22, 2022 · PreprintBioengineering

Interleukin 17 and senescence regulate the foreign body response

L. Chung, D. Maestas, A. Lebid, A. Mageau, G. D. Rosson, X. Wu, M. T. Wolf, A. Tam, X. Wang, I. Vanderzee, J. I. Andorko, R. Narain, K. Sadtler, H. Fan, D. Cihakova, , J. Elisseeff

This study identifies IL17 and senescence as regulators of the foreign body response, showing their roles in fibrosis and potential as therapeutic targets.

bioRxiv · Apr 11, 2019Immunology