Author

K. Thakkar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

A. C. Koong· 1 shared A. Chawla· 1 shared A. Diep· 1 shared A. J. Giaccia· 1 shared A. Rothrauff· 1 shared A. V. Joglekar· 1 shared C. Cenik· 1 shared C. Jia· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. C. Koong

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Temporal dynamics and genomic programming of plasma cell fates

G. K. M. Vijay, M. Zhou, K. Thakkar, A. Rothrauff, A. Chawla, D. Chen, L. Lau, P. Habib, K. Chetal, P. Chhibbar, J. Fan, J. Das, A. V. Joglekar, L. Borghesi, N. Salomonis, , H. Singh

This study identifies a novel PC transition state and shows that long-lived plasma cells arise from late-phase GC responses through TIGIT-dependent clonal expansion.

bioRxiv · Aug 27, 2023 · PreprintImmunology

Developing High-Affinity Decoy Receptor Optimized for Multiple Myeloma and Diffuse Large B Cell Lymphoma Treatment

Y. R. Miao, K. Thakkar, C. Cenik, D. Jiang, K. Mizuno, C. Jia, G. C. Li, H. Zhao, A. Diep, J. Y. Xu, X. E. Zhang, T. T. C. Yang, M. Liedtke, P. Abidi, W.-s. Leung, , A. J. Giaccia

This paper develops an engineered sBCMA-Fc fusion protein with enhanced binding affinity to APRIL and BAFF, showing improved antitumor activity against multiple myeloma and diffuse large B cell lymphoma in preclinical models.

bioRxiv · May 3, 2021Cancer Biology