Author

K. Chetal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Approach:experimental assay· 5 Research Focus:differential expression· 4 Organism:mouse· 3 Assay:scRNA-seq· 3 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

N. Salomonis· 4 shared A. Bertero· 1 shared A. Chawla· 1 shared A. H. Chan· 1 shared A. H. Jobe· 1 shared A. Kulkarni· 1 shared A. M. Fenix· 1 shared A. Rothrauff· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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4 shared papersImmunology

N. Salomonis

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Temporal dynamics and genomic programming of plasma cell fates

G. K. M. Vijay, M. Zhou, K. Thakkar, A. Rothrauff, A. Chawla, D. Chen, L. Lau, P. Habib, K. Chetal, P. Chhibbar, J. Fan, J. Das, A. V. Joglekar, L. Borghesi, N. Salomonis, , H. Singh

This study identifies a novel PC transition state and shows that long-lived plasma cells arise from late-phase GC responses through TIGIT-dependent clonal expansion.

bioRxiv · Aug 27, 2023 · PreprintImmunology

Gain-of-function cardiomyopathic mutations in RBM20 rewire splicing regulation and re-distribute ribonucleoprotein granules within processing bodies

A. M. Fenix, Y. Miyaoka, A. Bertero, S. Blue, M. J. Spindler, K. K. B. Tan, J. A. Perez-Bermejo, A. H. Chan, S. J. Mayer, T. Nguyen, C. R. Russell, P. Lizarraga, A. Truong, P.-L. So, A. Kulkarni, , N. Salomonis

This study investigates how RBM20 mutations affect splicing and ribonucleoprotein granules in cardiomyopathy, revealing distinct pathogenic mechanisms between missense and knockout mutations.

bioRxiv · Jun 2, 2021Cell Biology

A potent myeloid response is rapidly activated in the lungs of premature Rhesus macaques exposed to intra-uterine inflammation

C. M. Jackson, M. Demmert, S. Mukherjee, T. Isaacs, J. Gray, P. Senthamaraikannan, P. Presicce, K. Chetal, N. Salomonis, L. A. Miller, A. H. Jobe, S. G. Kallapur, W. J. Zacharias, I. P. Lewkowich, H. Deshmukh, C. A. Chougnet

This study investigates the fetal lung immune response to intra-uterine inflammation in Rhesus macaques, finding a rapid myeloid cell activation and cytokine-driven inflammation.

bioRxiv · May 28, 2021Immunology

Stiffness Regulates Intestinal Stem Cell Fate

S. He, L. Peng, W. Kang, P. Cheung, T. Xu, M. Mana, C. Y. Park, H. Wang, S. Imada, J. O. Russell, J. Wang, R. Wang, Z. Zhou, K. Chetal, E. Stas, , N. Saeidi

This study shows that matrix stiffness affects intestinal stem cell fate by reducing Lgr5high ISCs and promoting differentiation into goblet cells, mediated by YAP nuclear translocation.

bioRxiv · Mar 15, 2021Cell Biology

Single-nucleus RNA-seq identifies transcriptional heterogeneity in multinucleated skeletal myofibers

M. Petrany, C. Swoboda, C. Sun, K. Chetal, X. Chen, M. Weirauch, N. Salomonis, D. Millay

The paper uses snRNA-seq to analyze transcriptional diversity in multinucleated skeletal myofibers, revealing distinct myonuclear populations and novel gene markers.

bioRxiv · Apr 14, 2020Cell Biology