Author

K. Tierney

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 6

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 6 Organism:non-human primate· 2 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

N. Tailor· 5 shared D. Safronetz· 4 shared L. Banadyga· 4 shared M. Chan· 4 shared R. Vendramelli· 4 shared S. He· 4 shared D. Kobasa· 3 shared J. Audet· 3 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersMicrobiology

N. Tailor

Mutual co-authors in cluster

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6 papers

Recent·Most cited

The rVSV-EBOV vaccine provides limited cross-protection against Sudan virus in guinea pigs

W. Cao, S. He, G. Liu, H. Schulz, K. Emeterio, M. Chan, K. Tierney, K. Azaransky, G. Soule, N. Tailor, A. Salawudeen, R. Nichols, J. Fusco, D. Safronetz, L. Banadyga

This study shows that the rVSV-EBOV vaccine provides limited cross-protection against Sudan virus in guinea pigs, while the rVSV-SUDV vaccine offers complete protection.

bioRxiv · Nov 11, 2022Microbiology

An S1 subunit vaccine and combination adjuvant (COVAC-1) elicits robust protection against SARS-CoV-2 challenge in African green monkeys

L. Garnett, K. Tran, M. Chan, K. Tierney, Z. Schiffman, J. Audet, J. Lew, C. Meilleur, M. Chan, K. Manguiat, N. Tailor, R. Vendramelli, Y. Deschambault, G. Beaudoin-Bussieres, C. Bourassa, , D. Falzarano

COVAC-1, an S1 subunit vaccine with adjuvant, protects African green monkeys from SARS-CoV-2 challenge by reducing viral load and pathology in the respiratory tract.

bioRxiv · Jun 16, 2022 · PreprintMicrobiology

Single immunization with recombinant ACAM2000 vaccinia viruses expressing the spike and the nucleocapsid proteins protect hamsters against SARS-CoV-2 caused clinical disease

J. Cao, Y. Deschambault, J. Lynch, B. Warner, K. Tierney, D. Huynh, R. Vendramelli, N. Tailor, S. Booth, B. Sajesh, K. Frost, K. LeBlanc, C. Layne, L. Lin, D. Beniac, , D. Kobasa

This study shows that a single immunization with a vaccinia virus expressing both SARS-CoV-2 spike and nucleocapsid proteins protects hamsters better than expressing either protein alone.

bioRxiv · Dec 2, 2021Microbiology

Exposure route, sex, and age influence disease outcome in a golden Syrian hamster model of SARS-CoV-2 infection

B. D. Griffin, B. M. Warner, M. Chan, E. J. Mendoza, N. Tailor, L. Banadyga, A. Leung, S. He, A. S. Boese, J. Audet, W. Cao, E. Moffat, L. Garnett, K. Tierney, K. N. Tran, , D. Kobasa

This study investigates how exposure route, sex, and age affect SARS-CoV-2 pathogenesis in golden Syrian hamsters, finding significant differences in disease outcomes.

bioRxiv · Jun 12, 2021 · PreprintMicrobiology

North American deer mice are susceptible to SARS-CoV-2

B. D. Griffin, M. Chan, N. Tailor, E. J. Mendoza, A. Leung, B. M. Warner, A. T. Duggan, E. Moffat, S. He, L. Garnett, K. N. Tran, L. Banadyga, A. Albietz, K. Tierney, J. Audet, , D. Kobasa

This study shows North American deer mice can be infected and transmit SARS-CoV-2, suggesting they may serve as a potential reservoir for the virus.

bioRxiv · Jul 25, 2020Microbiology

Two-antibody pan-ebolavirus cocktail confers broad therapeutic protection in ferrets and nonhuman primates

Z. A. Bornholdt, A. S. Herbert, C. E. Mire, S. He, R. W. Cross, A. Z. Wec, D. M. Abelson, J. B. Geisbert, R. M. James, M. N. Rahim, W. Zhu, V. Borisevich, L. Banadyga, B. M. Gunn, K. N. Agans, , J. M. Dye

This paper demonstrates that a two-antibody cocktail (MBP134AF) provides broad therapeutic protection against multiple ebolaviruses in ferrets and nonhuman primates.

bioRxiv · Aug 19, 2018Microbiology