Author

B. M. Gunn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Organism:non-human primate· 1

Frequent Co-Authors

A. S. Herbert· 3 shared G. Alter· 3 shared J. M. Dye· 3 shared L. M. Walker· 3 shared A. Z. Wec· 2 shared D. H. Kim· 2 shared D. M. Abelson· 2 shared E. Goodwin· 2 shared

Activity by Year

2018-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersMicrobiology

A. S. Herbert

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

An Engineered Antibody with Broad Protective Efficacy in Murine Models of SARS and COVID-19

C. G. Rappazzo, L. V. Tse, C. I. Kaku, D. Wrapp, M. Sakharkar, D. Huang, L. M. Deveau, T. J. Yockachonis, A. S. Herbert, M. B. Battles, C. M. O'Brien, M. E. Brown, J. C. Geoghegan, J. Belk, L. Peng, , L. M. Walker

This study engineers an antibody, ADG-2, that broadly neutralizes SARS-CoV and SARS-CoV-2 in mice, offering protection against respiratory disease and viral replication.

bioRxiv · Nov 17, 2020 · PreprintImmunology

Antibody against envelope protein from human endogenous retrovirus activates neutrophils in systemic lupus erythematosus

M. Tokuyama, B. M. Gunn, A. Venkataraman, Y. M. Kong, I. Kang, M. Townsend, K. Costenbader, G. Alter, A. Iwasaki

The paper identifies an endogenous retrovirus envelope protein, ERV-K102, elevated in SLE patients, which is activated by SLE IgG to promote neutrophil activation and NET formation.

bioRxiv · Sep 20, 2019Immunology

Human antibody cocktail deploys multiple functions to confer pan-ebolavirus protection

A. Z. Wec, Z. A. Bornholdt, S. He, A. S. Herbert, E. Goodwin, A. S. Wirchnianski, B. M. Gunn, Z. Zhang, W. Zhu, G. Liu, D. M. Abelson, C. L. Moyer, R. K. Jangra, R. M. James, R. R. Bakken, , K. Chandran

This paper develops a human antibody cocktail, MBP134, that provides broad protection against multiple ebolaviruses, showing enhanced efficacy in guinea pigs compared to individual antibodies.

bioRxiv · Aug 20, 2018Microbiology

Two-antibody pan-ebolavirus cocktail confers broad therapeutic protection in ferrets and nonhuman primates

Z. A. Bornholdt, A. S. Herbert, C. E. Mire, S. He, R. W. Cross, A. Z. Wec, D. M. Abelson, J. B. Geisbert, R. M. James, M. N. Rahim, W. Zhu, V. Borisevich, L. Banadyga, B. M. Gunn, K. N. Agans, , J. M. Dye

This paper demonstrates that a two-antibody cocktail (MBP134AF) provides broad therapeutic protection against multiple ebolaviruses in ferrets and nonhuman primates.

bioRxiv · Aug 19, 2018Microbiology