Author

K. Vousden

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

A. Clear· 1 shared A. D'Avola· 1 shared A. Gunawan· 1 shared A. Hedley· 1 shared A. Hock· 1 shared B. Kruspig· 1 shared C. Dick· 1 shared C. I. Wittke· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperImmunology

A. Clear

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

p53 and TIGAR promote redox control to protect against metabolic dysfunction-associated steatohepatitis

C. I. Wittke, E. C. Cheung, D. Athineos, N. Clements, L. Butler, M. Hughes, V. Morrison, D. Watt, K. Blyth, K. Vousden, T. J. Humpton

This study shows that p53 and TIGAR protect against MASH by controlling redox balance, preventing ROS accumulation, fibrosis, and inflammation.

bioRxiv · May 20, 2024Cancer Biology

PHGDH is required for germinal center formation and is a therapeutic target in MYC-driven lymphoma

A. D'Avola, N. Legrave, M. Tajan, P. Chakravarty, R. Shearer, H. King, E. Cheung, A. Clear, A. Gunawan, L. Zhang, L. James, J. MacRae, J. Gribben, D. Calado, K. Vousden, J. Riches

This study identifies PHGDH as essential for germinal center formation and shows its inhibition reduces lymphoma progression and improves survival.

bioRxiv · Nov 11, 2021Immunology

The ERBB network facilitates KRAS-driven lung tumorigenesis

B. Kruspig, T. Monteverde, S. Neidler, A. Hock, E. Kerr, C. Nixon, W. Clark, A. Hedley, C. Dick, K. Vousden, C. Martins, D. Murphy

This study shows that the ERBB network is required for KRAS-driven lung tumorigenesis and that inhibiting it enhances MEK inhibitor efficacy in treating such cancers.

bioRxiv · Apr 9, 2018Cancer Biology