Author

Z. Granot

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:host-pathogen & immune response· 3 Research Focus:cancer & tumor microenvironment· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

O. Yajuk· 2 shared T. Fainsod-Levi· 2 shared A. Chatziioannou· 1 shared A. Granit· 1 shared A. Jensen· 1 shared A. M. Rubinstein· 1 shared A. Meirovitz· 1 shared A. Obiedat· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

O. Yajuk

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Neutrophils impose strong selective pressure against PfEMP1 variants implicated in cerebral malaria

T. Zelter, J. Strahilevitz, K. Simantov, O. Yajuk, A. Jensen, R. Dzikowski, Z. Granot

The paper shows neutrophils kill P. falciparum blood stages via ICAM-1 and PfEMP1 variants linked to cerebral malaria.

bioRxiv · May 9, 2021 · PreprintMicrobiology

Mapping cellular subpopulations within triple negative breast cancer tumors provides a tool for cancer sensitization to radiotherapy

H. Alkhatib, A. M. Rubinstein, S. Vasudevan, E. Flashner-Abramson, S. Stefansky, S. Oguche, T. Peretz-Yablonsky, A. Granit, Z. Granot, I. Ben-Porath, K. Sheva, A. Meirovitz, N. Kravchenko-Balasha

This study identifies two subpopulations in irradiated TNBC tumors that expand post-RT and shows that targeting both improves radiotherapy sensitivity.

bioRxiv · Jan 7, 2021Cancer Biology

The PD-L1/PD-1 Axis Blocks Neutrophil Cytotoxicity In Cancer

M. Gershkovitz, O. Yajuk, T. Fainsod-Levi, Z. Granot

This study shows that blocking the PD-L1/PD-1 axis enhances neutrophil cytotoxicity and tumor cell apoptosis, independent of adaptive immunity.

bioRxiv · Feb 28, 2020Immunology

Novel IRE1-dependent proinflammatory signaling controls tumor infiltration by myeloid cells.

J. Obacz, J. Archambeau, P. J. Le Reste, R. Pineau, K. Barroso, E. Vlachavas, K. Voutetakis, T. Fainsod-Levi, A. Obiedat, Z. Granot, B. Tirosh, J. Samal, A. Pandit, J. Patterson, Q. Zheng, , e. chevet

This study identifies an IRE1-dependent proinflammatory signaling pathway in glioblastoma that promotes tumor invasion, angiogenesis, and myeloid cell infiltration.

bioRxiv · Jan 11, 2020Cancer Biology